Endocrine Abstracts

Foetal exposure to a diabetic intra-uterine environment is known to impair metabolic processes with long term consequences, a phenomenon termed foetal programming. However, the mechanisms involved has not been completely understood. Fructose feeding has been used to induce type 2 diabetes in animal models. This study aims to investigate if stress mechanism is involved in the foetal programming of diabetic pregnancies. Twenty-four female rats were randomly divided into two grou...

Maternal stress is commonly cited as a potential cause for idiopathic pregnancy loss (Knackstedt et al., 2005). However, the mechanisms through which stress affects implantation and pregnancy are yet to be totally deciphered. This study was designed to determine the effect of predator-induced psychosocial stress on implantation and pregnancy in rat. Cycling rats (n=48) at proestrus phase were paired overnight with sexually experienced male in ratio 2:1. Following conf...